Lisinopril 20 mg / Hydrochlorothiazide 25 mg Tablets is included in the Pill Pass Discount Drug List at Pill Pals Pharmacy. This educational article summarizes key FDA-label topics for patients, caregivers, and prescribers who want a plain-language overview before speaking with a physician or pharmacist.
Drug Name
Lisinopril 20 mg / Hydrochlorothiazide 25 mg Tablets
FDA Labeled Indications
Lisinopril and hydrochlorothiazide combination tablets are FDA-labeled for hypertension in patients for whom combination therapy is appropriate.
Contraindications
Contraindications include hypersensitivity to either component, history of ACE inhibitor-related angioedema, hereditary or idiopathic angioedema, anuria, sulfonamide hypersensitivity in labeled products, and coadministration with aliskiren in patients with diabetes.
Warnings
Warnings include fetal toxicity in pregnancy, angioedema, low blood pressure, kidney impairment, high or low potassium, dehydration, electrolyte imbalance, gout, photosensitivity, and rare acute angle-closure glaucoma.
Precautions
Monitor blood pressure, kidney function, potassium, sodium, and uric acid. Use caution with kidney disease, liver disease, diabetes, gout, diuretics, NSAIDs, lithium, potassium products, and other blood pressure medicines.
Adverse Reactions
Adverse reactions may include dizziness, cough, headache, fatigue, increased urination, low blood pressure, electrolyte changes, rash, and kidney laboratory changes.
Pill Pass Discount Drug List Notes
Availability, quantity limits, manufacturer selection, and final dispensing decisions may depend on prescription requirements, clinical appropriateness, inventory, and applicable law. This article is informational and is not a substitute for individualized medical advice, diagnosis, treatment, or the full FDA-approved labeling for the dispensed product.
Related Pill Pass Discount Drug List Articles
For related medications on the same Pill Pass Discount Drug List, you may also review Lisinopril 10 mg / Hydrochlorothiazide 12.5 mg Tablets, Lisinopril 20 mg / Hydrochlorothiazide 12.5 mg Tablets, Loratadine 10 mg Tablets, and Losartan 25 mg Tablets.
Source note: this article is written as a patient-friendly summary of FDA labeling topics available through DailyMed and related FDA labeling resources. Manufacturer-specific labeling can vary, so patients should rely on the medication guide, package insert, prescriber instructions, and pharmacist counseling for their specific product.
Lisinopril 20 mg / Hydrochlorothiazide 25 mg Tablets is on the Pill Pass List. This information is accurate as of May 13, 2026. If you would like more information on this medication, please contact your Physician or Pharmacist.



