Metformin 500 mg Immediate Release Tablets is included in the Pill Pass Discount Drug List at Pill Pals Pharmacy. This educational article summarizes key FDA-label topics for patients, caregivers, and prescribers who want a plain-language overview before speaking with a physician or pharmacist.
Drug Name
Metformin 500 mg Immediate Release Tablets
FDA Labeled Indications
Metformin immediate-release tablets are FDA-labeled as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients with type 2 diabetes mellitus when appropriate by age and product labeling.
Contraindications
Contraindications include severe kidney impairment, acute or chronic metabolic acidosis including diabetic ketoacidosis, and hypersensitivity to metformin.
Warnings
Warnings include lactic acidosis, especially with kidney impairment, certain imaging contrast procedures, surgery, hypoxic states, excessive alcohol intake, liver impairment, and acute heart failure or shock.
Precautions
Monitor kidney function before and during therapy. Use caution with contrast imaging, surgery, dehydration, alcohol, liver disease, heart failure, and drugs affecting renal function or metformin exposure.
Adverse Reactions
Adverse reactions may include diarrhea, nausea, vomiting, gas, abdominal discomfort, weakness, headache, metallic taste, low vitamin B12, and, rarely, lactic acidosis.
Pill Pass Discount Drug List Notes
Availability, quantity limits, manufacturer selection, and final dispensing decisions may depend on prescription requirements, clinical appropriateness, inventory, and applicable law. This article is informational and is not a substitute for individualized medical advice, diagnosis, treatment, or the full FDA-approved labeling for the dispensed product.
Related Pill Pass Discount Drug List Articles
For related medications on the same Pill Pass Discount Drug List, you may also review Metformin 1,000 mg Immediate Release Tablets, Memantine 10 mg Tablets, Methimazole 5 mg Tablets, and Memantine 5 mg Tablets.
Source note: this article is written as a patient-friendly summary of FDA labeling topics available through DailyMed and related FDA labeling resources. Manufacturer-specific labeling can vary, so patients should rely on the medication guide, package insert, prescriber instructions, and pharmacist counseling for their specific product.
Metformin 500 mg Immediate Release Tablets is on the Pill Pass List. This information is accurate as of May 13, 2026. If you would like more information on this medication, please contact your Physician or Pharmacist.



