Naproxen 220 mg Immediate Release Tablets is included in the Pill Pass Discount Drug List at Pill Pals Pharmacy. This educational article summarizes key FDA-label topics for patients, caregivers, and prescribers who want a plain-language overview before speaking with a physician or pharmacist.
Drug Name
Naproxen 220 mg Immediate Release Tablets
FDA Labeled Indications
Naproxen is FDA-labeled for pain and inflammation, including conditions such as arthritis, musculoskeletal pain, dysmenorrhea, and other painful inflammatory conditions depending on the product.
Contraindications
Contraindications include hypersensitivity to naproxen or other NSAIDs, a history of asthma or allergic-type reactions after aspirin or NSAID use, and use in the setting of coronary artery bypass graft surgery.
Warnings
Warnings include increased risk of serious cardiovascular thrombotic events, heart attack, stroke, gastrointestinal bleeding, ulceration, perforation, kidney injury, liver injury, high blood pressure, fluid retention, and serious skin reactions.
Precautions
Use the lowest effective dose for the shortest appropriate duration. Use caution with anticoagulants, antiplatelets, corticosteroids, SSRIs/SNRIs, ACE inhibitors, ARBs, diuretics, kidney disease, heart disease, pregnancy, and older age.
Adverse Reactions
Adverse reactions may include stomach pain, heartburn, nausea, dizziness, swelling, increased blood pressure, rash, kidney changes, and gastrointestinal bleeding.
Pill Pass Discount Drug List Notes
Availability, quantity limits, manufacturer selection, and final dispensing decisions may depend on prescription requirements, clinical appropriateness, inventory, and applicable law. This article is informational and is not a substitute for individualized medical advice, diagnosis, treatment, or the full FDA-approved labeling for the dispensed product.
Related Pill Pass Discount Drug List Articles
For related medications on the same Pill Pass Discount Drug List, you may also review Naproxen 250 mg Immediate Release Tablets, Naproxen 375 mg Immediate Release Tablets, Naproxen 500 mg Immediate Release Tablets, and Multivitamins (Pill Pals Brand).
Source note: this article is written as a patient-friendly summary of FDA labeling topics available through DailyMed and related FDA labeling resources. Manufacturer-specific labeling can vary, so patients should rely on the medication guide, package insert, prescriber instructions, and pharmacist counseling for their specific product.
Naproxen 220 mg Immediate Release Tablets is on the Pill Pass List. This information is accurate as of May 13, 2026. If you would like more information on this medication, please contact your Physician or Pharmacist.



