Spironolactone 25 mg Tablets is included in the Pill Pass Discount Drug List at Pill Pals Pharmacy. This educational article summarizes key FDA-label topics for patients, caregivers, and prescribers who want a plain-language overview before speaking with a physician or pharmacist.
Drug Name
Spironolactone 25 mg Tablets
FDA Labeled Indications
Spironolactone is FDA-labeled for heart failure, hypertension, edema associated with heart failure, cirrhosis or nephrotic syndrome, and primary hyperaldosteronism.
Contraindications
Contraindications include hyperkalemia, Addison's disease, and conditions where potassium is already dangerously high; labeling also includes hypersensitivity and significant renal impairment in some circumstances.
Warnings
Warnings include high potassium, kidney function changes, low blood pressure, endocrine effects, and tumor findings in animal studies.
Precautions
Monitor potassium, kidney function, blood pressure, and volume status. Use caution with ACE inhibitors, ARBs, NSAIDs, potassium supplements, salt substitutes, trimethoprim, digoxin, lithium, and kidney disease.
Adverse Reactions
Adverse reactions may include high potassium, dizziness, breast tenderness or enlargement, menstrual changes, nausea, vomiting, diarrhea, headache, and rash.
Pill Pass Discount Drug List Notes
Availability, quantity limits, manufacturer selection, and final dispensing decisions may depend on prescription requirements, clinical appropriateness, inventory, and applicable law. This article is informational and is not a substitute for individualized medical advice, diagnosis, treatment, or the full FDA-approved labeling for the dispensed product.
Related Pill Pass Discount Drug List Articles
For related medications on the same Pill Pass Discount Drug List, you may also review Tadalafil 2.5 mg Tablets *, Sotalol 120 mg Tablets, Tadalafil 5 mg Tablets *, and Sotalol 80 mg Tablets.
Source note: this article is written as a patient-friendly summary of FDA labeling topics available through DailyMed and related FDA labeling resources. Manufacturer-specific labeling can vary, so patients should rely on the medication guide, package insert, prescriber instructions, and pharmacist counseling for their specific product.
Spironolactone 25 mg Tablets is on the Pill Pass List. This information is accurate as of May 13, 2026. If you would like more information on this medication, please contact your Physician or Pharmacist.



