Spironolactone 25 mg Tablets is included in the Pill Pass Discount Drug List at Pill Pals Pharmacy. This educational article summarizes key FDA-label topics for patients, caregivers, and prescribers who want a plain-language overview before speaking with a physician or pharmacist.

Drug Name

Spironolactone 25 mg Tablets

FDA Labeled Indications

Spironolactone is FDA-labeled for heart failure, hypertension, edema associated with heart failure, cirrhosis or nephrotic syndrome, and primary hyperaldosteronism.

Contraindications

Contraindications include hyperkalemia, Addison's disease, and conditions where potassium is already dangerously high; labeling also includes hypersensitivity and significant renal impairment in some circumstances.

Warnings

Warnings include high potassium, kidney function changes, low blood pressure, endocrine effects, and tumor findings in animal studies.

Precautions

Monitor potassium, kidney function, blood pressure, and volume status. Use caution with ACE inhibitors, ARBs, NSAIDs, potassium supplements, salt substitutes, trimethoprim, digoxin, lithium, and kidney disease.

Adverse Reactions

Adverse reactions may include high potassium, dizziness, breast tenderness or enlargement, menstrual changes, nausea, vomiting, diarrhea, headache, and rash.

Pill Pass Discount Drug List Notes

Availability, quantity limits, manufacturer selection, and final dispensing decisions may depend on prescription requirements, clinical appropriateness, inventory, and applicable law. This article is informational and is not a substitute for individualized medical advice, diagnosis, treatment, or the full FDA-approved labeling for the dispensed product.

Related Pill Pass Discount Drug List Articles

For related medications on the same Pill Pass Discount Drug List, you may also review Tadalafil 2.5 mg Tablets *, Sotalol 120 mg Tablets, Tadalafil 5 mg Tablets *, and Sotalol 80 mg Tablets.

Source note: this article is written as a patient-friendly summary of FDA labeling topics available through DailyMed and related FDA labeling resources. Manufacturer-specific labeling can vary, so patients should rely on the medication guide, package insert, prescriber instructions, and pharmacist counseling for their specific product.

Spironolactone 25 mg Tablets is on the Pill Pass List. This information is accurate as of May 13, 2026. If you would like more information on this medication, please contact your Physician or Pharmacist.

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