Amitriptyline 75 mg Tablets — Generic For Elavil — Rising Pharma

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Amitriptyline hydrochloride tablets are a prescription medicine used for the relief of symptoms of depression. The label notes that endogenous depression is more likely to be helped than other depressive states.

This medicine is an antidepressant with sedative effects. It is not approved for use in pediatric patients, and it is not recommended for patients under 12 years of age.

The label warns that antidepressants can be associated with worsening depression, suicidal thoughts or behavior, or unusual changes in behavior, especially early in treatment or when the dose is changed. Families and caregivers should watch closely and report concerning changes to the prescriber.

Amitriptyline hydrochloride tablets may interact with many other medicines and should be used cautiously in people with certain medical conditions, including seizure history, urinary retention, angle-closure glaucoma, cardiovascular disorders, and impaired liver function.

Storage Information

Protect the patient's airway, establish an intravenous line and initiate gastric decontamination. Store at 20º to 25ºC (68º to 77ºF); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].

Key Counseling Points

• Take this medicine only as prescribed.
• Read the Medication Guide and ask questions if anything is unclear.
• Watch for worsening depression, suicidal thoughts, unusual behavior changes, agitation, irritability, insomnia, or mood changes, especially early in treatment or after dose changes.
• Tell the prescriber right away if symptoms of serotonin syndrome occur, such as agitation, hallucinations, fast heartbeat, fever, tremor, stiffness, or diarrhea.
• Do not use with monoamine oxidase inhibitors (MAOIs); the label lists this as a contraindication.
• Tell the prescriber about all other medicines, including SSRIs, SNRIs, triptans, fentanyl, lithium, tramadol, buspirone, St. Johnu2019s Wort, cimetidine, and alcohol.
• Use caution when driving or operating machinery because the medicine may impair mental and/or physical abilities.
• Report signs of low sodium such as headache, confusion, weakness, memory problems, or unsteadiness.
• Use caution if you have glaucoma, urinary retention, seizures, heart disease, or liver problems, as noted in the label.
• Keep the medicine out of reach of potentially suicidal patients; the label advises prescribing the smallest feasible quantity.

Helpful Patient Education

Amitriptyline hydrochloride tablets are a prescription tricyclic antidepressant used for the relief of symptoms of depression. The DailyMed label describes it as an antidepressant with sedative effects and notes important safety information about mood changes, suicidality, serotonin syndrome, and medicine interactions.

This product information is intended for pharmacy education and should be used alongside the official labeling. Patients should review the Medication Guide and discuss any questions, side effects, or interacting medicines with their prescriber or pharmacist.

Medication Summary last generated: 2026-07-09 03:18:15