Amoxicillin 500 mg / Clavulanate 125 mg Combination Tablets — Generic For Augmentin — Micro Labs

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Amoxicillin and clavulanate potassium tablets are an oral antibiotic medicine that combines amoxicillin, a penicillin-class antibacterial, with clavulanate potassium, a beta-lactamase inhibitor. The label says this combination helps broaden amoxicillin’s activity against some bacteria that would otherwise be resistant.

These tablets are indicated for certain infections in adults and pediatric patients caused by susceptible bacteria, including lower respiratory tract infections, acute bacterial otitis media, sinusitis, skin and skin structure infections, and urinary tract infections. The label also says they should not be used when testing shows the bacteria are susceptible to amoxicillin alone and do not produce beta-lactamase.

The tablet strengths listed are 250 mg/125 mg, 500 mg/125 mg, and 875 mg/125 mg. The 875 mg/125 mg tablets are scored. The 250 mg/125 mg tablet should not be substituted for the 250 mg/62.5 mg chewable tablet, and two 250 mg/125 mg tablets should not be substituted for one 500 mg/125 mg tablet.

Storage Information

protects amoxicillin from degradation by some beta-lactamase enzymes and extends the antibacterial spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin. STORAGE AND HANDLING Amoxicillin and Clavulanate Potassium Tablets, USP:   250 mg/125 mg Tablets:  White to off-white colored, capsule shaped, biconvex, film-coated tablets, debossed with “I 05” on one side and plain on the other side. Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].

Key Counseling Points

• Take this medicine only as prescribed for the infection listed by the label.
• It may be taken without regard to meals, but taking it at the start of a meal may help reduce stomach upset.
• Tell a healthcare professional about any history of serious allergy to penicillins, cephalosporins, or other beta-lactam antibiotics.
• Do not use if you have a history of cholestatic jaundice or hepatic dysfunction linked to amoxicillin-clavulanate.
• Get medical attention for signs of an allergic reaction, severe rash, or other worsening skin reaction.
• Report diarrhea, especially if it is severe, persistent, or occurs after antibiotic use.
• Tell a healthcare professional if you have liver disease or renal impairment, since dose guidance may differ in severe cases.
• Do not substitute this tablet with the chewable 250 mg/62.5 mg product.
• Tell a healthcare professional if you take probenecid, oral anticoagulants, allopurinol, or oral contraceptives.
• Use caution if there is a history of mononucleosis, since the label says this medicine should not be administered in that setting.

Helpful Patient Education

Amoxicillin and clavulanate potassium tablets are a prescription oral antibacterial product used for certain infections caused by susceptible bacteria. The label describes this combination as amoxicillin plus clavulanate potassium, which is included to help extend amoxicillin’s antibacterial activity against some beta-lactamase–producing organisms.

Available tablet strengths include 250 mg/125 mg, 500 mg/125 mg, and 875 mg/125 mg. Label information also highlights important precautions, including allergy risk, possible liver problems, diarrhea related to Clostridioides difficile, and several medication interaction considerations.

Medication Summary last generated: 2026-07-10 02:49:04