Cyproheptadine 4 mg Tablets — Generic For Periactin — Unichem

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Cyproheptadine hydrochloride tablets are an antihistaminic and antiserotonergic medicine available as 4 mg oral tablets. The label describes it as a serotonin and histamine antagonist with anticholinergic and sedative effects.

This medicine is indicated for certain allergy-related conditions, including perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild allergic skin reactions such as urticaria and angioedema, cold urticaria, dermatographism, and as adjunctive therapy for anaphylactic reactions after the acute manifestations have been controlled.

The label says cyproheptadine should not be used in newborn or premature infants, nursing mothers, or people with certain conditions such as angle-closure glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, bladder neck obstruction, pyloroduodenal obstruction, or hypersensitivity to cyproheptadine or similar drugs. It also warns that the medicine may cause sedation and can affect mental alertness.

Storage Information

Dispense in a well-closed container as defined in the USP, with a child-resistant closure (as required). STORAGE Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature.

Key Counseling Points

• This medicine is an antihistamine and antiserotonin agent used for certain allergy-related conditions.
• It may cause sedation, sleepiness, dizziness, or decreased mental alertness.
• Be careful with driving or operating machinery until you know how this medicine affects you.
• Alcohol and other CNS depressants may have additive effects with cyproheptadine.
• The label warns that antihistamines can occasionally cause excitation, especially in young children.
• Tell a healthcare professional about use of MAO inhibitors, since they can prolong and intensify anticholinergic effects.
• Use caution if there is a history of bronchial asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.
• Possible adverse effects listed on the label include dry mouth, blurred vision, constipation, urinary retention, rash, and weight gain.
• Overdosage can cause either central nervous system depression or stimulation, especially in pediatric patients.
• Seek urgent help for serious symptoms such as convulsions, breathing problems, severe drowsiness, or signs of anaphylactic shock.

Helpful Patient Education

Cyproheptadine hydrochloride tablets USP are 4 mg oral tablets described on the DailyMed label as an antihistaminic and antiserotonergic agent. The product is used for several allergy-related conditions, including allergic rhinitis, allergic conjunctivitis, urticaria, angioedema, cold urticaria, and dermatographism. The label also describes use as adjunctive therapy for anaphylactic reactions after acute symptoms are controlled.

This pharmacy education content summarizes key label information, including contraindications, warnings, adverse reactions, and dosing ranges for adults and children age 2 years and older. Common label warnings include sedation, reduced mental alertness, and additive effects with alcohol and other CNS depressants.

Medication Summary last generated: 2026-07-17 03:00:23