Pantoprazole 40 mg Enteric Coated Tablets — Generic For Protonix

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Pantoprazole sodium delayed-release tablets are a proton pump inhibitor (PPI) used for short-term treatment of erosive esophagitis associated with GERD, maintenance of healing of erosive esophagitis in adults, and long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome.

The tablets are taken by mouth and should be swallowed whole, with or without food. Do not split, chew, or crush the tablets. If a dose is missed, the label says to take it as soon as possible unless it is almost time for the next dose; do not take two doses at the same time.

The label lists serious risks that have been reported with PPIs, including kidney inflammation, diarrhea related to C. difficile, bone fracture, severe skin reactions, lupus-like reactions, low vitamin B-12 with long-term use, low magnesium, and fundic gland polyps. Common adverse reactions in adults include headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia.

Pantoprazole sodium should not be used with rilpivirine-containing products, and the label notes interactions with some other medicines and diagnostic tests.

Storage Information

STORAGE AND HANDLING How Supplied Pantoprazole sodium delayed-release tablets, USP 20 mg are yellow color, oval biconvex delayed-release tablets imprinted with G72 (black ink) on one side and plain on other side. Storage Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. store pantoprazole sodium delayed-release tablets? Store pantoprazole sodium delayed-release tablets at room temperature between 68°F to 77°F (20°C to 25°C).

Key Counseling Points

• Swallow the delayed-release tablets whole; do not split, chew, or crush them.
• The tablets may be taken with or without food.
• If a dose is missed, take it as soon as possible unless it is almost time for the next dose.
• Do not take two doses at the same time.
• Tell your health care provider about all medicines you take, especially rilpivirine-containing products, warfarin, clopidogrel, methotrexate, and medicines that depend on stomach acid for absorption.
• Watch for signs of a serious allergic reaction or severe skin reaction, such as swelling, trouble breathing, rash, or blistering, and get medical help right away if they occur.
• Contact a health care provider if diarrhea does not improve, because the label warns about C. difficile-associated diarrhea.
• Report symptoms that could suggest low magnesium, such as muscle spasms, cramps, irregular heartbeat, or seizures.
• Long-term use has been linked in the label to low vitamin B-12, bone fracture risk, and fundic gland polyps.
• The label says to use the lowest dose and shortest duration appropriate for the condition being treated.

Helpful Patient Education

Pantoprazole sodium delayed-release tablets are a proton pump inhibitor (PPI) used for short-term treatment of erosive esophagitis associated with GERD, maintenance of healing of erosive esophagitis in adults, and long-term treatment of pathological hypersecretory conditions including Zollinger-Ellison syndrome. The tablets are designed for oral use and should be swallowed whole.

Educational information based on the DailyMed label also notes important safety considerations, including possible serious skin, kidney, infection-related, and mineral-related adverse reactions, along with several drug interactions and laboratory test interferences. Review the label for approved uses, dosing, and administration instructions.

Medication Summary last generated: 2026-07-09 02:45:35