Promethazine 12.5 mg Tablets — Generic For Phenergan

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Promethazine Hydrochloride Tablets are an antihistamine medicine used by mouth. The label says they can help with allergy symptoms, motion sickness, nausea and vomiting, and sedation before or after surgery or during labor.

This medicine may cause drowsiness and can affect the ability to drive, ride a bike, or operate machinery. Alcohol and other medicines that slow the central nervous system can make these effects worse.

The label says promethazine tablets must not be used in children under 2 years of age because of the risk of serious breathing problems. It is also contraindicated in comatose states, in people with a known allergy to promethazine or other phenothiazines, and for lower respiratory tract symptoms such as asthma.

Storage Information

Store at 20°C to 25°C (68°F to 77°F) [See USP Controlled Room Temperature].

Key Counseling Points

• May cause marked drowsiness or impair thinking and physical abilities.
• Do not drink alcohol unless a healthcare professional says it is safe.
• Use caution with other medicines that cause sleepiness, including sedatives, narcotics, tranquilizers, and some antidepressants.
• Do not use in children under 2 years of age.
• Report involuntary muscle movements to a healthcare professional.
• Avoid prolonged exposure to the sun.
• Tell a healthcare professional about glaucoma, enlarged prostate, stomach or intestinal blockage, bladder blockage, heart disease, liver problems, breathing problems, sleep apnea, or seizures.
• Inform a healthcare professional about all prescription, nonprescription, vitamin, and herbal products being taken.
• Take caution with activities like driving or operating machinery until the effects are known.

Helpful Patient Education

Promethazine Hydrochloride Tablets are an oral antihistamine described on the DailyMed label for use in allergy symptoms, motion sickness, nausea and vomiting, and sedation. The label also includes important safety information about drowsiness, slowed breathing risk, and interactions with alcohol and other central nervous system depressants.

This pharmacy product information is based on the manufacturer’s DailyMed labeling and is intended to help explain common uses, precautions, and counseling points for promethazine hydrochloride tablets, including the need to avoid use in children under 2 years of age.

Medication Summary last generated: 2026-07-12 02:52:04