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Allopurinol 100 mg Tablets — Generic For Zyloprim — TEVA

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Allopurinol 100 mg Tablets — Generic For Zyloprim — TEVA is available through Pill Pals Pharmacy with cash-pay pharmacy pricing and free shipping where available. Prescription required.

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Description

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prescription required

Allopurinol 100 mg Tablets is available by prescription only. Go ahead and place your purchase. After making payment, we will ensure that a valid prescription is received from your prescriber.

Drug Label Highlights

Source: This information is taken from the official DailyMed drug label page when available. It is provided for educational purposes and is not a substitute for pharmacist counseling, prescriber instructions, or the full official labeling.

These highlights do not include all the information needed to use ALLOPURINOL TABLETS safely and effectively. See full prescribing information for ALLOPURINOL TABLETS.

ALLOPURINOL tablets, for oral use

Initial U.S. Approval:1966

Indications And Usage

Allopurinol Tablets is a xanthine oxidase inhibitor indicated for the management of:

Adult patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy) (1)

Adult and pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels (1)

Adult patients with recurrent calcium oxalate calculi whose daily uric acid excretion exceeds 800 mg/day in male patients and 750 mg/day in female patients, despite lifestyle changes (1)

Limitations of Use

Allopurinol Tablets is not recommended for the treatment of asymptomatic hyperuricemia. (1)

Dosage And Administration

Gout: Prior to initiating treatment assess serum uric acid level, complete blood count, chemistry panel, liver and kidney function tests. Prophylactic treatment for gout flares is recommended. (2.1, 2.2)

Hyperuricemia Associated with Cancer Therapy: The recommended dosage is:

Recurrent Calcium Oxalate Calculi: The recommended initial dosage in patients with normal kidney function is 200 mg to 300 mg orally daily. (2.5)

Dosage in Patients with Renal Impairment: See FPI for dosage modifications in patients with renal impairment. (2.6)

Dosage Forms And Strengths

Tablets: 100 mg and 300 mg, scored (3)

Contraindications

Known hypersensitivity to allopurinol or to any of the ingredients of allopurinol tablets. (4)

Warnings And Precautions

  • Skin Rash and Hypersensitivity: Allopurinol has been associated with serious and sometimes fatal dermatological reactions. Discontinue Allopurinol Tablets at the first appearance of skin rash or other signs of hypersensitivity reaction. (5.1)
  • Gout Flares: May occur during initiation of treatment. Concurrent prophylactic treatment with colchicine or anti-inflammatory agents is recommended. (5.2)
  • Nephrotoxicity: Allopurinol may affect kidney function. Patients with decreased kidney function require lower doses of Allopurinol Tablets. (5.3)
  • Hepatoxicity: Cases of reversible hepatotoxicity have occurred. If signs and symptoms of hepatotoxicity develop, evaluate liver function. (5.4)
  • Myelosuppression: Bone marrow suppression has been reported with allopurinol. (5.5)
  • Potential Effect on Driving and Use of Machinery: Drowsiness, somnolence and dizziness have been reported in patients taking allopurinol. (5.6)
  • Skin Rash and Hypersensitivity: Allopurinol has been associated with serious and sometimes fatal dermatological reactions. Discontinue Allopurinol Tablets at the first appearance of skin rash or other signs of hypersensitivity reaction. (5.1)
  • Gout Flares: May occur during initiation of treatment. Concurrent prophylactic treatment with colchicine or anti-inflammatory agents is recommended. (5.2)
  • Nephrotoxicity: Allopurinol may affect kidney function. Patients with decreased kidney function require lower doses of Allopurinol Tablets. (5.3)
  • Hepatoxicity: Cases of reversible hepatotoxicity have occurred. If signs and symptoms of hepatotoxicity develop, evaluate liver function. (5.4)
  • Myelosuppression: Bone marrow suppression has been reported with allopurinol. (5.5)
  • Potential Effect on Driving and Use of Machinery: Drowsiness, somnolence and dizziness have been reported in patients taking allopurinol. (5.6)

Skin Rash and Hypersensitivity: Allopurinol has been associated with serious and sometimes fatal dermatological reactions. Discontinue Allopurinol Tablets at the first appearance of skin rash or other signs of hypersensitivity reaction. (5.1)

Gout Flares: May occur during initiation of treatment. Concurrent prophylactic treatment with colchicine or anti-inflammatory agents is recommended. (5.2)

Nephrotoxicity: Allopurinol may affect kidney function. Patients with decreased kidney function require lower doses of Allopurinol Tablets. (5.3)

Hepatoxicity: Cases of reversible hepatotoxicity have occurred. If signs and symptoms of hepatotoxicity develop, evaluate liver function. (5.4)

Myelosuppression: Bone marrow suppression has been reported with allopurinol. (5.5)

Potential Effect on Driving and Use of Machinery: Drowsiness, somnolence and dizziness have been reported in patients taking allopurinol. (5.6)

Adverse Reactions

Most common adverse reactions (incidence > 1%) are nausea, diarrhea, and increase in liver function tests. (6)

To report SUSPECTED ADVERSE REACTIONS, contact Teva at 1-888-838-2872 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Drug Interactions

The following drugs may increase the risk of serious skin reactions: bendamustine, thiazide diuretics, ampicillin and amoxicillin. (7.1)

Capecitabine: Avoid concomitant use. (7.2)

Mercaptopurine or Azathioprine: Reduce mercaptopurine or azathioprine dose as recommended in the respective prescribing information. (7.2)

Pegloticase: Discontinue and refrain from initiating treatment with allopurinol tablets. (7.2)

See FPI for complete list of significant drug interactions. (7.2)

Use In Specific Populations

Pregnancy: May cause fetal harm. (8.1)

Lactation: Advise not to breastfeed. (8.2)

See 17 for PATIENT COUNSELING INFORMATION.

Revised: 4/2024

View Full DailyMed Label View DailyMed PDF

DailyMed highlights last updated: 2026-06-24 22:34:08

Additional information

Size/Count

30 Count
Dose/Strength

100 MG
Form

Tablet

Medication Guide

Official DailyMed Drug Label Information

This product has a DailyMed drug label PDF from the National Library of Medicine.

View / Download PDF View on DailyMed

  • Source: DailyMed, National Library of Medicine
  • DailyMed Label: ALLOPURINOL TABLET [ACTAVIS PHARMA, INC.]
  • Matched NDC: 0591-5543-01
  • Published Date: May 13, 2026

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Allopurinol Tablets are a xanthine oxidase inhibitor used to manage adults with signs and symptoms of gout, some patients receiving cancer therapy that raises uric acid, and certain adults with recurrent calcium oxalate stones when uric acid excretion remains high despite lifestyle changes. The product is not recommended for treating asymptomatic hyperuricemia.

The label says treatment for gout may be started after baseline testing, and gout flares can happen when therapy begins. If a flare occurs, the tablets do not need to be stopped; flare treatment may be given at the same time. Patients are advised to take allopurinol after meals if tolerated and to maintain fluid intake as directed in the label.

Serious skin reactions and hypersensitivity can occur, and the label says to stop the medicine and seek medical attention promptly if a rash develops. The label also warns about kidney problems, liver problems, blood count changes, and drowsiness or dizziness. Use in pregnancy may cause fetal harm, and the label advises not to breastfeed.

Storage Information

Storage and Handling Store at 20°C to 25°C (68°F to 77°F) [See USP Controlled Room Temperature].

Key Counseling Points

  • Use this medicine only as directed; the dose is based on the reason it is prescribed and, in some cases, kidney function.
  • For gout, a flare can happen when treatment starts. The label says to continue allopurinol if a flare occurs and manage the flare as directed.
  • Stop taking the medicine and get medical attention right away if you develop a rash or other signs of hypersensitivity.
  • Tell your healthcare provider about all medicines you take, especially bendamustine, ampicillin, amoxicillin, thiazide diuretics, mercaptopurine, azathioprine, capecitabine, pegloticase, warfarin, cyclosporine, theophylline, or uricosuric drugs.
  • The label warns that drowsiness, somnolence, and dizziness can occur; use caution with driving or machinery until you know how it affects you.
  • Drink fluids as directed in the label to support urine output and help reduce the risk of kidney stone formation.
  • Take the tablets after meals if they are better tolerated.
  • Do not double a dose if a dose is missed.
  • The label advises not to breastfeed, and it says the medicine may cause fetal harm in pregnancy.

Helpful Patient Education

Allopurinol Tablets are a prescription medicine used to help manage gout, certain cases of high uric acid related to cancer therapy, and recurrent calcium oxalate stones in selected patients with high uric acid excretion. It is a xanthine oxidase inhibitor, and the label says it is not recommended for asymptomatic hyperuricemia.

DailyMed labeling also warns about serious skin reactions, kidney and liver effects, blood count changes, and possible drowsiness or dizziness. Patients should follow the prescribed dosing instructions, report rash or hypersensitivity symptoms promptly, and review interacting medicines with a healthcare professional.

Medication Summary last generated: 2026-06-19 07:59:37

Allopurinol 100 mg Tablets --- Generic For Zyloprim --- TEVA may require patient-specific counseling based on your prescription, directions, allergies, medical history, and other medications.

This Medication Guide section is provided for general educational purposes only. It does not replace the official medication guide, patient information leaflet, counseling from your pharmacist, or medical advice from your prescriber.

Please read all information provided with your prescription. Contact Pill Pals Pharmacy or your prescriber with questions before using this medication.

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