Journal Article Summary
The article investigates the resistance patterns of urinary Escherichia coli (E. coli) in cats and dogs in the Midwestern United States, focusing on two commonly used antibiotics: amoxicillin and amoxicillin-clavulanate. Understanding these resistance patterns is crucial for veterinarians as it helps guide effective treatment for urinary tract infections (UTIs) in pets. Antibiograms, which summarize local bacterial resistance data, are important tools for improving antimicrobial stewardship and ensuring that pets receive the most appropriate and effective medications.
The study analyzed urine samples from 143 cats and 640 dogs collected between 2013 and 2017. It found that none of the E. coli isolates from cats were susceptible to amoxicillin-clavulanate or amoxicillin, while 53% of dog isolates were susceptible to amoxicillin and 92% to amoxicillin-clavulanate. The researchers noted a significant difference in susceptibility between the two species, suggesting that the breakpoints used to determine resistance may need reevaluation, particularly for cats, to improve treatment options.
Limitations of the study include its retrospective design, which may have affected the consistency of urine sample handling and the potential inclusion of repeat samples from the same animals. Additionally, the study did not differentiate between clinical and subclinical infections, which could influence the applicability of the findings. Pet owners should discuss these results with their veterinarians to understand the best treatment options for their pets, especially if their pets have a history of UTIs or prior antibiotic treatments.
Medication Safety Note
This journal article summary is provided for educational purposes only and is not medical advice. Always consult a licensed healthcare professional before starting, stopping, or changing any medication.
Article Cited
- KuKanich Kate, Lubbers Brian, Salgado Brianna. Amoxicillin and amoxicillin‐clavulanate resistance in urinary Escherichia coli antibiograms of cats and dogs from the Midwestern United States. Journal of Veterinary Internal Medicine 2019. DOI: 10.1111/jvim.15674. PMID: 31777977. PMCID: PMC6979265.
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