Journal Article Summary
The article investigates a new method for measuring famotidine, a medication commonly used to treat stomach and duodenal ulcers and gastric reflux disease. Famotidine works by blocking H2 receptors, and accurate measurement of its concentration in pharmaceutical formulations is crucial for ensuring proper dosing and effectiveness. Traditional methods for analyzing famotidine have limitations, such as sensitivity and cost, which makes developing a more efficient and reliable technique important for both healthcare providers and patients.
The researchers developed a spectrophotometric method that utilizes a charge transfer complex formed between famotidine and Ortho-chloranil. They tested this method on various concentrations of famotidine in both pure and pharmaceutical forms, achieving a reliable detection range of 2 to 28 µg/ml. The study found that the method demonstrated high accuracy, with a recovery rate of approximately 99.56% and a low detection limit, making it suitable for practical applications in pharmaceutical analysis.
However, the study does have limitations, including the need for careful handling of reagents and the specific conditions required for optimal results, such as temperature and pH. Patients and caregivers should be aware that while this method shows promise for accurate famotidine measurement, it is essential to consult healthcare professionals regarding any medication adjustments or concerns. Discussing the implications of this research with a healthcare provider can help ensure safe and effective use of famotidine in treatment plans.
Medication Safety Note
This journal article summary is provided for educational purposes only and is not medical advice. Always consult a licensed healthcare professional before starting, stopping, or changing any medication.
Article Cited
- Al Samarrai Shatha Y., AlZubaidi Radhi, Al-Ansari Nadhir. Charge transfer complex-based spectrophotometric analysis of famotidine in pure and pharmaceutical dosage forms. Scientific Reports 2024. DOI: 10.1038/s41598-024-54402-4. PMID: 38351288. PMCID: PMC10864395.
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