Journal Article Summary
The article investigates the interaction between Silexan, an oral lavender oil preparation known for its anxiety-reducing effects, and the efficacy of a common oral contraceptive, MicrogynonĀ®, which contains ethinyl estradiol and levonorgestrel. This research is significant because many women who experience anxiety may also use oral contraceptives, and understanding any potential interactions is crucial for ensuring effective contraception and managing anxiety. Given the prevalence of anxiety disorders among women of childbearing age, it is essential to assess whether Silexan could impact the effectiveness of these contraceptives.
In this study, 24 healthy women aged 21 to 37 participated in a double-blind, randomized, placebo-controlled crossover trial. Each participant took either Silexan or a placebo alongside MicrogynonĀ® for two cycles, with blood samples taken to measure hormone levels. The results showed that Silexan did not significantly affect the pharmacokinetics of ethinyl estradiol and levonorgestrel, as the confidence intervals for hormone levels remained within the acceptable range. Although there was a slight delay in the peak concentration of levonorgestrel, it did not impact the overall effectiveness of the contraceptive.
The study has some limitations, including a small sample size and the exclusion of women who smoke heavily, which could affect the generalizability of the findings. While the results indicate that Silexan is safe to use with MicrogynonĀ®, patients should still consult their healthcare providers before combining any medications or supplements. Discussing any concerns about anxiety treatment and contraceptive efficacy with a healthcare professional is important to ensure safe and effective management of both conditions.
Medication Safety Note
This journal article summary is provided for educational purposes only and is not medical advice. Always consult a licensed healthcare professional before starting, stopping, or changing any medication.
Article Cited
- Heger-Mahn Doris, Pabst GĆ¼nther, Dienel Angelika, SchlƤfke Sandra, Klipping Christine. No Interacting Influence of Lavender Oil Preparation Silexan on Oral Contraception Using an Ethinyl Estradiol/Levonorgestrel Combination. Drugs in R&D 2014. DOI: 10.1007/s40268-014-0065-5. PMID: 25319228. PMCID: PMC4269819.
Featured Pill Pals Product
OPill (O-Pill) Norgestrel Tablets 0.075 mg Daily Oral Contraceptive (Birth Control) --- Perrigo --- Over The Counter
OPill (O-Pill) Norgestrel Tablets 0.075 mg Daily Oral Contraceptive (Birth Control) ā Perrigo ā Over The Counter is available through Pill Pals Pharmacy with cash-pay pharmacy pricing and free shipping where available. This is an Over The Counter Product, so no prescription is required.However, your prescriber can still write for it as a prescription, if desired.
