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Nosocomial Transmission of Plasmodium falciparum Malaria, Spain, 2024 (Response)

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In Response: We appreciate the opportunity to respond to the letter from Dr. Perales (1) regarding our article on a case of nosocomial transmission of Plasmodium falciparum during a thyroid scintigraphy (2). The author of the letter proposes as an alternative mechanism the nosocomial transmission of the parasite by contact with blood on gloves not changed between patients. We respectfully disagree because the mechanism he proposes lacks scientific basis; no evidence of malaria transmission by such contact has been documented. On the contrary, nosocomial transmission of P. falciparum by parenteral route is well demonstrated, through blood transfusions, transplants (3), or invasive medical procedures involving exposure to contaminated blood (3), as occurred in our case (2).

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Manuel F. Liroa Romero, Maite Ruiz Pérez de Pipaón, Maria D. Navarro Amuedo, Jose M. Rubio Muñoz, Jose M. Jiménez-Hoyuela, and Jose M. Cisneros 

Author affiliation: University of Seville, Seville, Spain (M.F. Liroa Romero, M. Ruiz Pérez de Pipaón, M.D. Navarro Amuedo, J.M. Jiménez-Hoyuela, J.M. Cisneros); Hospital Universitario Virgen del Rocío, Seville (M.F. Liroa Romero, M. Ruiz Pérez de Pipaón, M.D. Navarro Amuedo, J.M. Jiménez-Hoyuela, J.M. Cisneros); CIBERINFEC Instituto de Salud Carlos III, Madrid, Spain (J.M. Rubio Muñoz, J.M. Cisneros)

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References

  1. Romero  MFL, de Pipaón  MRP, Amuedo  MDN, Rubio Muñoz  JM, Jiménez-Hoyuela  JM, Cisneros  JM. Nosocomial transmission of Plasmodium falciparum malaria, Spain, 2024. Emerg Infect Dis. 2025;31:1250–3.PubMedGoogle Scholar
  2. Romero  MFL, de Pipaón  MRP, Amuedo  MDN, Rubio Muñoz  JM, Jiménez-Hoyuela  JM, Cisneros  JM. Nosocomial transmission of Plasmodium falciparum malaria, Spain, 2024. Emerg Infect Dis. 2025;31:1250–3.PubMedGoogle Scholar
  3. Romero  MFL, de Pipaón  MRP, Amuedo  MDN, Rubio Muñoz  JM, Jiménez-Hoyuela  JM, Cisneros  JM. Nosocomial transmission of Plasmodium falciparum malaria, Spain, 2024. Emerg Infect Dis. 2025;31:1250–3. DOIPubMedGoogle Scholar

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Suggested citation for this article: Liroa Romero MF, Ruiz Pérez de Pipaón M, Navarro Amuedo MD, Rubio Muñoz JM, Jiménez-Hoyuela JM, Cisneros JM. Nosocomial transmission of Plasmodium falciparum malaria, Spain, 2024. Emerg Infect Dis. 2025 Sep [date cited]. https://doi.org/10.3201/eid3109.251210

DOI: 10.3201/eid3109.251210

Original Publication Date: August 20, 2025

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Table of Contents – Volume 31, Number 9—September 2025

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Nosocomial Transmission of Plasmodium falciparum Malaria, Spain, 2024 (Response)

Volume 31, Number 9—September 2025

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