Allopurinol 100 mg Tablets — Generic For Zyloprim — Avet

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Allopurinol tablets are taken by mouth and are used to manage certain conditions related to too much uric acid. The label says they are indicated for adults with signs and symptoms of gout, for adults and pediatric patients receiving cancer therapy that raises uric acid, and for adults with recurrent calcium oxalate stones in hyperuricosuric patients.

The label says allopurinol tablets are not recommended for treating asymptomatic hyperuricemia. Treatment may require dose changes based on kidney function, and the label recommends lab testing before starting allopurinol for gout, including uric acid level, blood counts, liver tests, and kidney tests.

Important safety warnings include serious skin reactions and hypersensitivity, gout flares when treatment starts, kidney problems, liver injury, and bone marrow suppression. The label also notes that drowsiness, sleepiness, and dizziness can happen.

If a rash or other signs of hypersensitivity occur, the label says to stop allopurinol immediately and seek medical attention. The label also says to keep up fluid intake as directed in the prescribing information and to follow monitoring instructions from the prescriber.

Storage Information

Storage and Handling  Store at 20°C to 25°C (USP Controlled Room Temperature) (68°F to 77°F) in a dry place. Dispense in a tight container as defined in the USP.

Key Counseling Points

• Take allopurinol by mouth exactly as directed on the prescription label.
• This medicine is used for gout, cancer-therapy-related high uric acid, and recurrent calcium oxalate stones in hyperuricosuric patients.
• It is not recommended for asymptomatic hyperuricemia.
• A gout flare can happen when treatment starts; the label says allopurinol does not need to be stopped if a flare occurs.
• Report any rash or other signs of hypersensitivity right away; the label says to stop the medicine immediately if these occur.
• Tell your prescriber about kidney or liver problems, because dose adjustments and monitoring may be needed.
• The label says allopurinol can cause drowsiness, somnolence, or dizziness; use caution with driving or machinery until you know how it affects you.
• The label recommends drinking enough fluids to maintain good urine output, especially during therapy.
• If you miss a dose, do not double the next dose.
• Tell your healthcare professional about all medicines you take, because allopurinol has important drug interactions.

Helpful Patient Education

Allopurinol tablets are an oral xanthine oxidase inhibitor used to help manage conditions associated with elevated uric acid, including gout, uric acid elevation during cancer therapy, and recurrent calcium oxalate stones in hyperuricosuric patients. The label also states that allopurinol tablets are not recommended for asymptomatic hyperuricemia.

Educational labeling highlights include the need for baseline and follow-up monitoring in some patients, dose adjustments for kidney impairment, and awareness of important safety issues such as serious skin reactions, gout flares, kidney effects, liver injury, and myelosuppression. Patients should follow the full prescribing information and their clinician’s directions for use and monitoring.

Medication Summary last generated: 2026-07-09 03:16:18