Cyproheptadine 4 mg Tablets — Generic For Periactin — Quagen

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Cyproheptadine hydrochloride tablets, USP are prescription-only tablets for oral use that contain 4 mg of cyproheptadine hydrochloride in each tablet. Cyproheptadine is described on the label as an antihistaminic and antiserotonergic agent with anticholinergic and sedative effects.

The tablets are indicated for several allergy-related conditions, including perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild allergic skin manifestations such as urticaria and angioedema, cold urticaria, dermatographism, and allergic reactions to blood or plasma. The label also lists use as adjunctive therapy for anaphylactic reactions after the acute manifestations have been controlled.

Important safety information includes warnings about sedation, decreased mental alertness, and additive effects with alcohol and other central nervous system depressants. The label also lists multiple contraindications, including use in newborn or premature infants, nursing mothers, and patients with certain eye, urinary, gastrointestinal, or prostate conditions.

The product contains lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate as inactive ingredients.

Storage Information

Dispense in a well-closed container as defined in the USP, with a child-resistant closure (as required). Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature].

Key Counseling Points

• This is a prescription-only medicine for oral use.
• Each tablet contains 4 mg of cyproheptadine hydrochloride.
• The label warns that the medicine may cause drowsiness, dizziness, or reduced mental alertness.
• Be careful with activities that require alertness and coordination, such as driving or operating machinery.
• Alcohol and other central nervous system depressants may have additive effects with this medicine.
• The label notes possible anticholinergic effects, including dry mouth and blurred vision.
• The label lists increased appetite/weight gain among reported adverse reactions.
• Do not use in newborn or premature infants.
• The label says safety and effectiveness in children under 2 years have not been established.
• Report serious or unusual reactions to a healthcare professional promptly.

Helpful Patient Education

Cyproheptadine hydrochloride tablets, USP are prescription antihistamine tablets available as 4 mg oral tablets. The DailyMed label describes cyproheptadine as a serotonin and histamine antagonist with anticholinergic and sedative effects and lists allergy-related indications such as allergic rhinitis, allergic conjunctivitis, urticaria, angioedema, cold urticaria, and dermatographism.

Label information also includes important safety details, including drowsiness, reduced mental alertness, and possible additive effects with alcohol and other CNS depressants. The tablets contain 4 mg of cyproheptadine hydrochloride and are supplied as white to off-white round tablets with the marked imprint described on the package labeling.

Medication Summary last generated: 2026-07-10 03:05:07