Glipizide 5 mg Tablets — Generic For Glucotrol — Advagen

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Glipizide tablets are an oral blood-glucose-lowering medicine in the sulfonylurea class. They are used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

The tablet works by stimulating insulin release from the pancreas, which depends on functioning beta cells. The label notes that some patients may not respond at first, or may later lose responsiveness to sulfonylurea drugs, including glipizide.

Glipizide tablets should not be used in people with type 1 diabetes mellitus or diabetic ketoacidosis. The label also warns that all sulfonylureas can cause severe hypoglycemia and that certain patients may be at higher risk.

Storage Information

STORAGE: Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [see USP Controlled Room Temperature].

Key Counseling Points

• Take glipizide tablets as part of a plan that includes diet and exercise.
• The label says glipizide is usually given about 30 minutes before a meal.
• Blood glucose should be monitored regularly; urine glucose may also be checked, and glycosylated hemoglobin may be useful.
• Learn the signs of hypoglycemia and how it is treated.
• Be aware that hypoglycemia may be more likely with missed meals, heavy exercise, alcohol use, or when taken with other glucose-lowering drugs.
• Tell a healthcare professional about all medicines being taken, because some drugs can increase or decrease glipizideu2019s effect.
• Glipizide should not be used in type 1 diabetes or diabetic ketoacidosis.
• If blood sugar control is lost during stress such as fever, trauma, infection, or surgery, the label notes that glipizide may need to be stopped and insulin may be needed.
• Report unusual symptoms such as rash, jaundice, dizziness, drowsiness, headache, or signs of low blood sugar.
• The label notes that elderly patients and those with liver or kidney problems may need cautious dosing.

Helpful Patient Education

Glipizide tablets are an oral sulfonylurea medicine used as an adjunct to diet and exercise to help improve glycemic control in adults with type 2 diabetes mellitus. The label describes glipizide as a blood-glucose-lowering drug that works by stimulating insulin release from the pancreas in people with functioning beta cells.

DailyMed label information also highlights important safety considerations, including the risk of hypoglycemia, possible drug interactions, and the need for regular blood glucose monitoring. Glipizide is not indicated for type 1 diabetes mellitus or diabetic ketoacidosis.

Medication Summary last generated: 2026-07-11 02:49:20