Hydrochlorothiazide 25 mg Tablets — Generic For Microzide — Unichem

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Hydrochlorothiazide tablets are a diuretic and antihypertensive medicine. They are used as add-on treatment for edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid and estrogen therapy, and certain kidney disorders. They are also used to manage hypertension, either alone or with other blood pressure medicines.

The label states that hydrochlorothiazide affects how the kidneys handle sodium, chloride, and water, which leads to increased urine output. It usually starts working within 2 hours after oral use, peaks in about 4 hours, and lasts about 6 to 12 hours.

The tablets contain hydrochlorothiazide in strengths of 12.5 mg, 25 mg, or 50 mg. Common inactive ingredients listed on the label include corn starch, FD&C Yellow #6, dibasic calcium phosphate, pregelatinized starch, colloidal silicon dioxide, lactose monohydrate, and magnesium stearate.

Storage Information

Dispense in a well-closed container as defined in the USP. Store at 20° to 25° C (68° to 77° F) [see USP Controlled Room Temperature].

Key Counseling Points

• Take hydrochlorothiazide exactly as directed on the label or by your prescriber.
• The medicine may increase urine output; the label says diuresis usually begins within 2 hours after oral use.
• Report symptoms that may suggest fluid or electrolyte imbalance, such as dry mouth, thirst, weakness, drowsiness, confusion, muscle cramps, nausea, or vomiting.
• The label warns that low potassium can occur and may be more likely with brisk diuresis or prolonged therapy.
• Be aware that dizziness or low blood pressure can occur, especially when taken with alcohol, barbiturates, narcotics, or other antihypertensive drugs.
• Tell a healthcare professional if you have a sulfonamide allergy, since hypersensitivity is a labeled contraindication.
• The label advises patients to protect skin from the sun and have regular skin cancer screening.
• Vision changes or eye pain need prompt attention because the label warns about acute myopia and secondary angle-closure glaucoma.
• If adverse reactions are moderate or severe, the label says dosage may need to be reduced or therapy withdrawn.
• Keep in mind the label notes periodic serum electrolyte checks may be needed during therapy.

Helpful Patient Education

Hydrochlorothiazide tablets are a prescription diuretic and antihypertensive used to help manage edema and high blood pressure. The DailyMed label describes use in edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid and estrogen therapy, as well as certain renal conditions and hypertension.

This medication can affect fluid and electrolyte balance, and the label includes warnings about low potassium, low sodium, dizziness, drug interactions, and rare eye or skin reactions. It is important to follow labeled directions and be aware of the potential adverse effects described in the product information.

Medication Summary last generated: 2026-07-06 02:50:58