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Metoprolol Tartrate (Immediate Release) 50 mg Tablets — Generic For Lopressor — Advagen

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Metoprolol Tartrate (Immediate Release) 50 mg Tablets — Generic For Lopressor — Advagen is available through Pill Pals Pharmacy with cash-pay pharmacy pricing and free shipping where available. Prescription required.

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Description

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prescription required

Metoprolol Tartrate (Immediate Release) 50 mg Tablets is available by prescription only. Go ahead and place your purchase. After making payment, we will ensure that a valid prescription is received from your prescriber.

Drug Label Highlights

Source: This information is taken from the official DailyMed drug label page when available. It is provided for educational purposes and is not a substitute for pharmacist counseling, prescriber instructions, or the full official labeling.

These highlights do not include all the information needed to use METOPROLOL TARTRATE TABLETS safely and effectively. See full prescribing information for METOPROLOL TARTRATE TABLETS.

METOPROLOL TARTRATE tablets, for oral use

Initial U.S. Approval: 1992

Indications And Usage

Metoprolol tartrate is a beta-adrenergic blocker indicated for the treatment of:

Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. (

1.1)

Angina Pectoris. (

1.2)

Myocardial Infarction, to reduce the risk of cardiovascular mortality when used in conjunction with intravenous metoprolol therapy in patients with definite or suspected acute myocardial infarction in hemodynamically stable patients. (

1.3)

Dosage And Administration

Administer once daily with food or after a meal. Titrate at weekly or longer intervals as needed and tolerated. (

2)

Hypertension: Recommended starting dosage is 100 mg daily, in single or divided doses. (

2.1)

Angina Pectoris: Recommended starting dosage is 100 mg daily, given as two divided doses. (

2.2)

Myocardial Infarction: The starting dosage depends upon tolerance of intravenous metoprolol, see full prescribing information. (

2.3)

Dosage Forms And Strengths

Metoprolol tartrate tablets: 25 mg, 37.5 mg, 50 mg, 75 mg and 100 mg. (

3)

Contraindications

Known hypersensitivity to product components. (

4)

Severe bradycardia: Greater than first degree heart block, or sick sinus syndrome without a pacemaker. (

4)

Cardiogenic shock or decompensated heart failure. (

4)

Warnings And Precautions

  • Abrupt cessation may exacerbate myocardial ischemia. ( 5.1)
  • Heart Failure: Worsening cardiac failure may occur. ( 5.2)
  • Bronchospastic Disease: Avoid beta-blockers. ( 5.3)
  • Pheochromocytoma: Initiate therapy with an alpha blocker. ( 5.4)
  • Major Surgery: Avoid initiation of high-dose extended-release metoprolol in patients undergoing non- cardiac surgery. Do not routinely withdraw chronic beta-blocker therapy prior to surgery. ( 5.5, 6.1)
  • Diabetes: May mask symptoms of hypoglycemia. ( 5.6)
  • Thyrotoxicosis: Abrupt withdrawal in patients with thyrotoxicosis might precipitate a thyroid storm. ( 5.7)
  • Peripheral Vascular Disease: Can aggravate symptoms of arterial insufficiency. ( 5.9)
  • Abrupt cessation may exacerbate myocardial ischemia. ( 5.1)
  • Heart Failure: Worsening cardiac failure may occur. ( 5.2)
  • Bronchospastic Disease: Avoid beta-blockers. ( 5.3)
  • Pheochromocytoma: Initiate therapy with an alpha blocker. ( 5.4)
  • Major Surgery: Avoid initiation of high-dose extended-release metoprolol in patients undergoing non- cardiac surgery. Do not routinely withdraw chronic beta-blocker therapy prior to surgery. ( 5.5, 6.1)
  • Diabetes: May mask symptoms of hypoglycemia. ( 5.6)
  • Thyrotoxicosis: Abrupt withdrawal in patients with thyrotoxicosis might precipitate a thyroid storm. ( 5.7)
  • Peripheral Vascular Disease: Can aggravate symptoms of arterial insufficiency. ( 5.9)

Abrupt cessation may exacerbate myocardial ischemia. (

5.1)

Heart Failure: Worsening cardiac failure may occur. (

5.2)

Bronchospastic Disease: Avoid beta-blockers. (

5.3)

Pheochromocytoma: Initiate therapy with an alpha blocker. (

5.4)

Major Surgery: Avoid initiation of high-dose extended-release metoprolol in patients undergoing non- cardiac surgery. Do not routinely withdraw chronic beta-blocker therapy prior to surgery. (

5.5,

6.1)

Diabetes: May mask symptoms of hypoglycemia. (

5.6)

Thyrotoxicosis: Abrupt withdrawal in patients with thyrotoxicosis might precipitate a thyroid storm. (

5.7)

Peripheral Vascular Disease: Can aggravate symptoms of arterial insufficiency. (

5.9)

Adverse Reactions

Most common adverse reactions: tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus, rash. (

6.1)

To report SUSPECTED ADVERSE REACTIONS, contact Advagen Pharma Ltd. at 866-488-0312 or FDA at 1-800-FDA-1088 or

www.fda.gov/medwatch.

Drug Interactions

Catecholamine-depleting drugs may have an additive effect when given with beta-blocking agents. (

7.1)

Patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction. (

7.2)

CYP2D6 Inhibitors are likely to increase metoprolol concentration. (

7.3)

Concomitant use of glycosides, clonidine, and diltiazem and verapamil with beta-blockers can increase the risk of bradycardia. (

7.4)

Beta-blockers including metoprolol, may exacerbate the rebound hypertension that can follow the withdrawal of clonidine. (

7.4)

Use In Specific Populations

Hepatic Impairment: Consider initiating Metoprolol tartrate therapy at low doses and gradually increase dosage to optimize therapy, while monitoring closely for adverse events. (

8.6)

See 17 for PATIENT COUNSELING INFORMATION.

Revised: 1/2026

View Full DailyMed Label View DailyMed PDF

DailyMed highlights last updated: 2026-06-24 22:43:14

Additional information

Size/Count

30 Count
Dose/Strength

50 MG
Form

Tablet

Medication Guide

Official DailyMed Drug Label Information

This product has a DailyMed drug label PDF from the National Library of Medicine.

View / Download PDF View on DailyMed

  • Source: DailyMed, National Library of Medicine
  • DailyMed Label: METOPROLOL TARTRATE TABLET, FILM COATED [ADVAGEN PHARMA LIMITED]
  • Matched NDC: 72888-005-01
  • Published Date: Jan 14, 2026

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Metoprolol tartrate tablets are a beta-blocker taken by mouth. The label says they are used to treat high blood pressure, long-term angina, and certain patients with acute myocardial infarction. Lowering blood pressure can reduce the risk of strokes and heart attacks.

The tablets should be taken once daily with food or right after a meal, and some uses may require divided doses. Dosing is adjusted gradually over weekly or longer intervals based on response and tolerability.

Do not stop metoprolol suddenly unless directed by the prescriber. Abrupt stopping may worsen chest pain and, in some cases, lead to a heart attack. The label also notes important cautions for people with heart failure, bronchospastic disease, diabetes, thyroid disease, and peripheral vascular disease.

Storage Information

store clinical stability before advancing the dose of Metoprolol tartrate [see Dosage and Administration (2)]. STORAGE AND HANDLING Metoprolol Tartrate Tablets, USP are available containing 25 mg, 37. Storage: Store at 20° to 25°C (68° to 77°F). Dispense in a tight, light-resistant container (USP) as defined in the USP using a child-resistant closure.

Key Counseling Points

  • Take metoprolol with food or right after a meal, as directed on your prescription.
  • Take it at the same time each day if your prescriber has you on a regular schedule.
  • Do not stop this medicine suddenly; the label warns that abrupt stopping can worsen angina or trigger heart problems.
  • If you are told to stop it, the dose should be reduced gradually over 1 to 2 weeks.
  • Tell your clinician if you have asthma or other bronchospastic disease, since beta-blockers are generally avoided and the lowest possible dose may be used if prescribed.
  • Let your clinician know if you have diabetes, because this medicine may mask early warning signs of low blood sugar.
  • Be aware that metoprolol can cause tiredness, dizziness, shortness of breath, low heart rate, low blood pressure, diarrhea, rash, or itching.
  • The label notes that some medicines can interact with metoprolol, including clonidine, diltiazem, verapamil, digitalis glycosides, and strong CYP2D6 inhibitors.
  • If you have a history of severe allergic reactions, tell your clinician, since beta-blockers may make treatment with epinephrine less effective.
  • Report symptoms such as very slow pulse, fainting, worsening heart failure, or wheezing promptly.

Helpful Patient Education

Metoprolol tartrate tablets are an oral beta-blocker available in multiple strengths, including 50 mg. According to the DailyMed label, this medicine is used for hypertension, angina pectoris, and certain patients with acute myocardial infarction. Dosing is individualized and may be adjusted over time based on response and tolerability.

This product page is intended to provide educational information about metoprolol tartrate from the manufacturer labeling. It includes basic use information, common adverse reactions, major warnings, and storage handling details from DailyMed for pharmacy reference.

Medication Summary last generated: 2026-07-19 02:42:05

Metoprolol Tartrate (Immediate Release) 50 mg Tablets --- Generic For Lopressor --- Advagen may require patient-specific counseling based on your prescription, directions, allergies, medical history, and other medications.

This Medication Guide section is provided for general educational purposes only. It does not replace the official medication guide, patient information leaflet, counseling from your pharmacist, or medical advice from your prescriber.

Please read all information provided with your prescription. Contact Pill Pals Pharmacy or your prescriber with questions before using this medication.

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