Cyproheptadine 4 mg Tablets — Generic For Periactin — Amneal

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Cyproheptadine Hydrochloride Tablets, USP are 4 mg oral tablets. Cyproheptadine is described on the label as an antihistaminic and antiserotonergic agent, and as a serotonin and histamine antagonist with anticholinergic and sedative effects.

The tablets are used for several allergy-related conditions, including perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild allergic skin reactions such as urticaria and angioedema, cold urticaria, dermatographism, and as adjunctive therapy for anaphylactic reactions after acute symptoms are controlled.

The label lists important warnings and precautions. Cyproheptadine may cause drowsiness, dizziness, and decreased mental alertness, and it may have additive effects with alcohol and other central nervous system depressants. It is contraindicated in newborn or premature infants, nursing mothers, and in people with certain conditions listed on the label, including angle-closure glaucoma and bladder or stomach outlet obstruction.

Storage Information

Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Dispense in a well-closed container as defined in the USP.

Key Counseling Points

• This medicine may cause drowsiness, dizziness, or sedation.
• Be careful with activities that require mental alertness or motor coordination, such as driving or operating machinery.
• Alcohol and other central nervous system depressants may have additive effects with this medicine.
• Antihistamines may occasionally cause excitation, especially in young children.
• Use caution if you have a history of bronchial asthma, increased eye pressure, hyperthyroidism, cardiovascular disease, or hypertension.
• The label states this drug should not be used in newborn or premature infants or in nursing mothers.
• Tell your healthcare provider about all medicines you take, especially monoamine oxidase inhibitors.
• Possible adverse reactions listed on the label include dry mouth, confusion, blurred vision, constipation, urinary retention, rash, and increased appetite/weight gain.

Helpful Patient Education

Cyproheptadine Hydrochloride Tablets, USP 4 mg are oral antihistamine tablets with antiserotonergic activity. According to the label, they are used for several allergy-related conditions, including allergic rhinitis, allergic conjunctivitis, urticaria, angioedema, cold urticaria, dermatographism, and as adjunctive therapy for anaphylactic reactions after the acute manifestations have been controlled.

This product is labeled with important safety information, including possible drowsiness, dizziness, and other central nervous system effects. The label also lists drug interaction cautions and contraindications, so patients should review the product labeling and speak with a healthcare professional about proper use.

Medication Summary last generated: 2026-06-19 14:19:04