Cyproheptadine 4 mg Tablets — Generic For Periactin — Quagen

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Cyproheptadine Hydrochloride Tablets, USP are oral 4 mg tablets. Cyproheptadine is described in the label as an antihistaminic and antiserotonergic agent, and it also has anticholinergic and sedative effects.

The tablets are indicated for certain allergic conditions, including perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild allergic skin reactions such as urticaria and angioedema, cold urticaria, dermatographism, and allergic reactions to blood or plasma. The label also lists use as adjunctive therapy for anaphylactic reactions after acute manifestations have been controlled.

The label warns that this medicine may cause drowsiness, dizziness, and reduced mental alertness. It also notes that alcohol and other central nervous system depressants can have additive effects with cyproheptadine.

Storage Information

Dispense in a well-closed container as defined in the USP, with a child-resistant closure (as required). Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature].

Key Counseling Points

• This medicine is an antihistamine and antiserotonergic agent used for certain allergic conditions.
• It may cause sedation, sleepiness, dizziness, or reduced alertness.
• Use caution with activities requiring mental alertness and motor coordination, such as driving or operating machinery.
• Alcohol and other CNS depressants may have additive effects with this medicine.
• The label notes that young children may sometimes have excitation rather than drowsiness.
• Do not use this medicine in newborn or premature infants.
• The label lists several conditions where use is contraindicated, including angle-closure glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, bladder neck obstruction, pyloroduodenal obstruction, and hypersensitivity to cyproheptadine or similar drugs.
• Use with caution in patients with asthma history, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.
• Adverse reactions reported with antihistamines include dry mouth, blurred vision, constipation, urinary retention, and rash.
• If there are concerns about overdose, the label describes serious symptoms such as central nervous system depression or stimulation, and atropine-like signs.

Helpful Patient Education

Cyproheptadine Hydrochloride Tablets, USP 4 mg are oral antihistamine tablets described on the label as having antihistaminic and antiserotonergic activity, with anticholinergic and sedative effects. The DailyMed labeling lists use for several allergic conditions, including allergic rhinitis, allergic conjunctivitis, urticaria, angioedema, dermatographism, and certain allergic reactions.

This product page information is based on the official label and includes key safety details such as the potential for drowsiness, dizziness, and reduced mental alertness, as well as listed contraindications, warnings, and possible adverse reactions. It is intended for educational use and should be read alongside the full product labeling.

Medication Summary last generated: 2026-07-05 12:26:38