Memantine 10 mg Tablets — Generic For Namenda — Upsher-Smith

Medication Summary

Medication Summary: This section summarizes DailyMed drug label information to make the label easier to understand. It is not a substitute for the official label, pharmacist counseling, prescriber instructions, or medical advice.

Overview

Memantine hydrochloride tablets are a prescription medicine taken by mouth for the treatment of moderate to severe dementia of the Alzheimer's type. The label says memantine is an NMDA receptor antagonist.

The recommended starting dose is 5 mg once daily, with increases in 5 mg steps at intervals of at least one week until the maintenance dose is reached. The dose shown to be effective in controlled clinical trials is 20 mg/day. Tablets may be taken with or without food.

If a dose is missed, the next dose should be taken as scheduled and not doubled. If memantine is not taken for several days, dosing may need to be restarted at lower doses and increased again.

Common side effects in clinical trials included dizziness, headache, confusion, and constipation. The label also says memantine should not be used in patients with known hypersensitivity to memantine hydrochloride or any excipients in the formulation.

Storage Information

STORAGE AND HANDLING Memantine hydrochloride tablets, USP 5 mg are tan, capsule-shaped, film-coated tablets with "12" debossed on one side and "832" on the other side. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. store memantine hydrochloride tablets? Store memantine hydrochloride tablets at room temperature between 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F).

Key Counseling Points

• Take memantine exactly as prescribed and follow the dose increases as directed.
• The tablet can be taken with or without food.
• If you miss one dose, do not take two doses at the next scheduled time.
• If you have not taken memantine for several days, ask about restarting at a lower dose and retitrating.
• Common side effects reported in studies included dizziness, headache, confusion, and constipation.
• Use caution if you have conditions that raise urine pH, since this may affect elimination of memantine.
• Tell your healthcare provider about all medicines you take, including other NMDA antagonists such as amantadine, ketamine, and dextromethorphan.
• The label says severe renal impairment may require a lower dose.
• The label says memantine should be used with caution in severe hepatic impairment.
• Report suspected side effects to your healthcare provider or the FDA MedWatch program.

Helpful Patient Education

Memantine hydrochloride tablets are an oral prescription medicine used for the treatment of moderate to severe dementia of the Alzheimer's type. The label describes memantine as an NMDA receptor antagonist and provides a stepwise dosing schedule that starts at 5 mg once daily and increases gradually to a maintenance dose.

This product page can help patients and caregivers understand key label information, including how memantine is taken, what to do if a dose is missed, common adverse reactions reported in trials, and important precautions for kidney and liver impairment and certain drug interactions.

Medication Summary last generated: 2026-07-19 02:38:32